1、 Overview
Sleep is very important to human body. About one third of a person's life is spent in sleep. Through sleep, we can eliminate fatigue, recover spirit and physical strength, and improve work and learning efficiency.
In 1906, R. Legendre and H. Pieron of the University of Paris published a discussion on the decomposition of toxins during sleep. In 1970, M. Monnier of Switzerland discovered the inducing substance of sleep, a hormone secreted by brain tissue. In 1984, J.R. PAPPENHEIMER of Harvard University in the United States found that the sleep inducing substance, the cytoplasmic peptide, was produced by the brain of mammals. On the one hand, it has the function of fever, and on the other hand, it has the function of enhancing the immune ability. Therefore, it is of great significance to develop a safe and effective functional food to improve sleep.
（1） , sleep function
1. Sleep can make the human body get enough rest, recover physical strength and energy, and keep a good awakening state after sleep. Compared with arousal, many physiological functions of human body have changed during sleep.
It is generally manifested in the following aspects:
(1) The sensory function of olfactory, visual, auditory and touch decreased;
(2) Skeletal muscle reflexes and muscle tension decrease;
(3) Accompanied by a series of changes in plant sexual function. example
For example, the heart beat slows down, the blood pressure drops, the pupil shrinks, the perspiration function strengthens, the muscle is in the complete relaxation state, the basic metabolism rate drops 10% ~ 20%.
2. Sleep can produce new cells, maintain energy and repair itself. Lack of sleep will lead to decreased resistance.
（2） , sleep rhythm
Biological rhythms are universal. When the period of wave is close to the period of earth rotation, it is called circadian rhythm. This rhythm is usually self-sustaining and non attenuating, which is the inherent and internal essence of organism - called "biological clock". The circadian rhythms are quite accurate when the circadian clock is free. In a large range, circadian rhythms are almost unaffected by temperature and insensitive to chemicals, but they are very sensitive to light. For human body, it is very important to maintain the normal sleep and wake cycle. Once these cycles are disrupted, they can cause serious sleep disorders.
The circadian rhythm of sleep disorder of sleep delay syndrome is relatively slow, and the patients can't fall asleep at normal time.
Another kind of sleep disorder is early sleep syndrome. Patients begin to feel sleepy at 8 p.m., but wake up at 1 or 2 a.m. many elderly people have this kind of trouble.
There is also a sleep disorder called non-24h sleep and wake-up cycle. The most obvious symptom of patients is that they are awake and sleep for too long, and their cycle can even reach 50h. Using time therapy, that is, using light to improve the circadian rhythm, can help the above patients to return to normal sleep mode.
（3） , generation of sleep
It is generally believed that sleep is an active process produced in the central nervous system, which is related to some specific structures in the central nervous system, as well as the role of some transmitters. The study of central neurotransmitters shows that the regulation of sleep and wakefulness is closely related to the dynamic changes of central neurotransmitters. Among them, 5-hydroxytryptamine is related to the induction and maintenance of sleep, while noradrenaline is related to the maintenance of wakefulness. Sleep makes the body rest. During sleep, the body basically blocks the connection with the surrounding environment. Many of the body's system activities will slowly decline during sleep, but at this time, the activities of clearing damaged cells, making new cells and repairing itself in the body are not weakened.
During sleep, the immune cells in human blood increased significantly, especially lymphocytes.
Insomnia is the most common and common sleep disorder. Insomniacs are either difficult to fall asleep, easy to wake up or wake up early, or sleep quality is low, sleep time is significantly reduced, or some of them have both. Short term insomnia can make people look haggard, often insomnia makes people speed up aging, serious insomnia is often accompanied by a series of pathological reactions such as mental depression, emotional fragility, and withdrawn personality. The normal rhythms of brain excitation and inhibition are disturbed, and the functional diseases of nervous system, neurasthenia, directly affect the physical and mental health of insomnia.
Sleep is important, but it's not that the longer you sleep, the better. Too much sleep can reduce the body's activity, and the unused excess fat can be stored in the body, thus inducing arteriosclerosis and other dangerous diseases.
（1） , melatonin
Its chemical name is N-acetyl-5-methoxytryptamine, also known as pinesin; Melatonin; melatonin.
1、 Overview
Sleep is very important to human body. About one third of a person's life is spent in sleep. Through sleep, we can eliminate fatigue, recover spirit and physical strength, and improve work and learning efficiency.
In 1906, R. Legendre and H. Pieron of the University of Paris published a discussion on the decomposition of toxins during sleep. In 1970, M. Monnier of Switzerland discovered the inducing substance of sleep, a hormone secreted by brain tissue. In 1984, J.R. PAPPENHEIMER of Harvard University in the United States found that the sleep inducing substance, the cytoplasmic peptide, was produced by the brain of mammals. On the one hand, it has the function of fever, and on the other hand, it has the function of enhancing the immune ability. Therefore, it is of great significance to develop a safe and effective functional food to improve sleep.
（1） , sleep function
1. Sleep can make the human body get enough rest, recover physical strength and energy, and keep a good awakening state after sleep. Compared with arousal, many physiological functions of human body have changed during sleep.
It is generally manifested in the following aspects:
(1) The sensory function of olfactory, visual, auditory and touch decreased;
(2) Skeletal muscle reflexes and muscle tension decrease;
(3) Accompanied by a series of changes in plant sexual function. example
For example, the heart beat slows down, the blood pressure drops, the pupil shrinks, the perspiration function strengthens, the muscle is in the complete relaxation state, the basic metabolism rate drops 10% ~ 20%.
2. Sleep can produce new cells, maintain energy and repair itself. Lack of sleep will lead to decreased resistance.
（2） , sleep rhythm
Biological rhythms are universal. When the period of wave is close to the period of earth rotation, it is called circadian rhythm. This rhythm is usually self-sustaining and non attenuating, which is the inherent and internal essence of organism - called "biological clock". The circadian rhythms are quite accurate when the circadian clock is free. In a large range, circadian rhythms are almost unaffected by temperature and insensitive to chemicals, but they are very sensitive to light. For human body, it is very important to maintain the normal sleep and wake cycle. Once these cycles are disrupted, they can cause serious sleep disorders.
The circadian rhythm of sleep disorder of sleep delay syndrome is relatively slow, and the patients can't fall asleep at normal time.
Another kind of sleep disorder is early sleep syndrome. Patients begin to feel sleepy at 8 p.m., but wake up at 1 or 2 a.m. many elderly people have this kind of trouble.
There is also a sleep disorder called non-24h sleep and wake-up cycle. The most obvious symptom of patients is that they are awake and sleep for too long, and their cycle can even reach 50h. Using time therapy, that is, using light to improve the circadian rhythm, can help the above patients to return to normal sleep mode.
（3） , generation of sleep
It is generally believed that sleep is an active process produced in the central nervous system, which is related to some specific structures in the central nervous system, as well as the role of some transmitters. The study of central neurotransmitters shows that the regulation of sleep and wakefulness is closely related to the dynamic changes of central neurotransmitters. Among them, 5-hydroxytryptamine is related to the induction and maintenance of sleep, while noradrenaline is related to the maintenance of wakefulness. Sleep makes the body rest. During sleep, the body basically blocks the connection with the surrounding environment. Many of the body's system activities will slowly decline during sleep, but at this time, the activities of clearing damaged cells, making new cells and repairing itself in the body are not weakened.
During sleep, the immune cells in human blood increased significantly, especially lymphocytes.
Insomnia is the most common and common sleep disorder. Insomniacs are either difficult to fall asleep, easy to wake up or wake up early, or sleep quality is low, sleep time is significantly reduced, or some of them have both. Short term insomnia can make people look haggard, often insomnia makes people speed up aging, serious insomnia is often accompanied by a series of pathological reactions such as mental depression, emotional fragility, and withdrawn personality. The normal rhythms of brain excitation and inhibition are disturbed, and the functional diseases of nervous system, neurasthenia, directly affect the physical and mental health of insomnia.
Sleep is important, but it's not that the longer you sleep, the better. Too much sleep can reduce the body's activity, and the unused excess fat can be stored in the body, thus inducing arteriosclerosis and other dangerous diseases.
（1） , melatonin
Its chemical name is N-acetyl-5-methoxytryptamine, also known as pinesin; Melatonin; melatonin.
